T-cell surface glycoprotein CD3 epsilon chain - ορισμός. Τι είναι το T-cell surface glycoprotein CD3 epsilon chain
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Τι (ποιος) είναι T-cell surface glycoprotein CD3 epsilon chain - ορισμός


T-cell surface glycoprotein CD3 epsilon chain         
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
CD3 epsilon; CD3ε; CD3e; CD3E; CD3E (gene)
CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11.
T-cell receptor         
  • Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.
MOLECULE FOUND ON THE SURFACE OF SOME IMMUNE CELLS
Alpha-beta T-cell antigen receptor; Genes, t-cell receptor; T-cell receptors; Receptors, antigen, t-cell; T-cell antigen receptors; TCRδ1; TCRd1; T cell receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR.
Variant surface glycoprotein         
  • Mechanisms of VSG switching in T. brucei: A. Structure of the expression site including the expression site associated genes (ESAG), 70 base pair repeat up-stream sequence, expressed VSG gene, and the telomere B. Mechanism of array VSG conversion: A silent VSG is copied from a subtelomeric VSG array into an ES, where it replaces the active VSG. C. Telomeric VSG conversion: A telomeric VSG (including 70 bp repeat sequence upstream and telomere downstream) replaces the active VSG in the ES D. Segmental VSG conversion: Sequence is copied from multiple inactive VSG genes and combined into a novel mosaic VSG that occupies the ES E. Transcriptional VSG switching: A non-recombination based mechanism that activates a new (previously silent) ES, while inactivating the previously active ES.
  • Structure of one of the N-terminal VSG variants. VSG genes have a largely conserved N-terminal secondary and tertiary structure (composed of two alpha-helices which form the dimerization interface, and which couple into a four helix bundle), while still allowing for variable primary sequence. This variable primary sequence allows for VSG to be antigenically distinct from one another, the crux to antigenic variation.
GLYCOPROTEINS ATTACHED TO THE SURFACE COAT OF TRYPANOSOMES
Variant surface glycoproteins, trypanosoma; Variable surface glycoproteins; Variable Surface Glycoprotein; Variable Surface Glycoproteins; Variant surface glycoproteins; Variant Surface Glycoprotein; Variant Surface Glycoproteins; Tb927.5.4730; Tb05.26C7.380; VSG protein; VSG proteins; Bloodstream Expression Site; Bloodstream expression site; Expression site associated gene; Expression Site Associated Gene; Variable surface glycoprotein; Invariant Surface Glycoprotein; Invariant surface glycoprotein
Variant surface glycoprotein (VSG) is a ~60kDa protein which densely packs the cell surface of protozoan parasites belonging to the genus Trypanosoma. This genus is notable for their cell surface proteins.